Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 175
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SALIC YLA MID.
sulphates eliminated by the urine, the drug being thus
capable of acting in some way as an antiseptic.
Therapeutic Applications.-Salacetol has been em-
ployed with good results as an intestinal antiseptic in
diarrhoea and similar disorders. This drug is partic-
ularly adapted for use in children, since it has been found
to be much less poisonous than salol; in fact, unlike the
latter remedy, salicylacetol contains no phenol. This new
agent has given satisfactory results also in the treatment
of subacute and chronic rheumatism.
Administration. - Salacetol may be administered
alone or in combination with castor oil, in single doses
of from 30 to 45 grains (2 to 3 grammes). For children
daily amounts of as high as 71 grains (0.50 gramme)
may be employed.
SALICYLAMID.
This amidogen compound, a derivative of salicylic
acid, is chiefly obtained by the action of concentrated
ammonia upon methyl salicylate or by the action of heat
upon the salicylate of ammonium. Salicylamid has the
formula
OH
C6H4 H
CONH2.
Physical Properties.-This drug, when pure, appears
in the form of colorless, tasteless, transparent plates
having a melting-point of 287.6 F. (142 C.).
Solubility.-This remedy is soluble in alcohol, chloro-
form, and ether, and in water in the proportion of I to
250 parts.
Therapeutic Applications.-Salicylamid is used for
the same purposes as salicylic acid, and is said to be a
safer and a more prompt and powerful analgesic than
the latter medicament. It has thus been employed,
with asserted good results, in the treatment of neuralgia
and ovarian pains, and also in chronic rheumatism andI75
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/174/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.