Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 176
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176 NOTES ON THE NE WER REMEDIES.
follicular tonsillitis. This drug is likewise alleged to
possess decided germicidal powers.
Administration.-The quantity of salicylamid to be
administered daily may be put down as 15 grains (I
gramme), given in single doses of from 3 to 5 grains
(o. 18 to 0.32 gramme).
SALIPYRIN.
The name saliyrin is given to a true salt (salicylate of
antipyrin) obtained from the interaction of antipyrin and
salicylic acid. It contains 57.7 per cent. of the first and
42.3 per cent. of the second agent. This new combina-
tion is represented by the formula C18H1RN204.
Physical Properties.-This salt appears as a white,
odorless, crystalline substance having a more or less
agreeable taste. When crystallized from alcoholic solu-
tions it has a melting-point of 196.7 F. (91.50 C.).
Solubility.-Salipyrin is freely soluble in alcohol and
benzenes, sparingly soluble in ether, and soluble in about
200 parts of water.
Therapeutic Applications.-This remedy is claimed
to be a good antipyretic and resolvent. It has been used
with success against sciatica and in acute and chronic
rheumatism. It is also said to have given satisfactory
results in the treatment of influenza and in those forms
of dysmenorrhoea which accompany the change of life.
Administration.-This drug may be given in the
form of powder, in cachets, or in capsules. The single
dose of salipyrin is 15 grains (I gramme), and it may be
repeated until 90 grains (6 grammes) are taken.
SALOL.
Salol is phenic ether of salicylic acid, or salicylate of
phenyl. It is represented by the formula
OH
C6H4OI-I
COOCH,.
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/175/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.