Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 151
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PELLE TIERIANE ANNA TE.- PENTAL.
PELLETIERINE TANNATE.
The alkaloid of the pomegranate-bark, or Punica gra-
natum, pelletierine (CsH,zNO), is a colorless liquid which
forms salts with the acids. The chief salts known are
the hydrobromate, the hydrocklorate, the sulphate, and
the tannate, the last one being represented by the formula
C8H13NO.C14H,009.
Physical Properties.-This salt is an odorless, yel-
lowish, hygroscopic powder having a pungent and astrin-
gent taste.
Solubility.-This drug is soluble in 8o parts of
alcohol and in 700 parts of water.
Therapeutic Applications.- Tannate of pelletierine
has been chiefly employed as an excellent and prompt
teniacide.
Administration.-This remedy is best given in single
doses of 23 grains (I.5 grammes) in about an ounce of
water, followed by a cathartic.
PENTAL.
This drug is the trimethylethylene or the beta-iso-
amylene, whose chemical composition is represented by
the formula (CH)2C.CH.,CH3., or CHx,,.
Physical Properties.-Pental is a colorless liquid
with a melting-point of Ioo.40 F. (380 C.) and a sp. gr.
of o.678. It is highly inflammable, burning with an
illuminating flame. It is exceedingly volatile, but does
not decompose on exposure to light or to the atmo-
sphere.
Solubility.-This drug is soluble in alcohol, ether,
and chloroform, but is insoluble in water.
Physiological Action.-Nervous System.-This agent
has general anaesthetic properties and a slight local in-
fluence. It seems to act centrally. The anaesthesia is
rapidly produced, but it also quickly disappears.
Circzulation.-Both the blood-pressure and the rate of
the pulse are depressed by pental. These phenomenaI5I
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/150/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.