Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 155
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PHENIDIN.NPHENOCOLL.
profuse cold sweating, a sluggish circulation-in fact, all
the symptoms of collapse. Dilatation of the pupil some-
times occurs. Red spots on the extremities and large
wheals have been observed after the use of phenacetin.
PHENIDIN.
This substance is allied to phenacetin, and is also
known as para-acetplcnitidin.
Therapeutic Applications. This remedy is lauded as
a valuable analgesic, being considered superior to anti-
pyrin.
Administration.-Plzenidin is given in single doses of
15 grains (I gramme); and may be repeated until three
or four doses are taken.
PHENOCOLL.
This new antipyretic remedy, closely allied to phenac-
etin, is obtained by the interaction of para-amido-phe-
notoll and glycocoll, its formula being
OC H,
C6\NH,COCH2NH2 + H2O.
The drug used in practical medicine is the hydrochloride
or zydrocklorate, and it is then represented as
OC2H5
NH,COCH2N HHC1.
Physical Properties.-This salt occurs as a white
crystalline powder. The water compound melts at
203 F. (92 C.), but the anhydrous base requires a
temperature of 212.9 F. (Ioo.50 C.).
Solubility.-This drug is readily soluble in water
and in alcohol, but only barely soluble in chloroform,
ether, and benzol.
Physiological Action.-Nervous System.-PhenocollI55
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/154/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.