Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 150
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150 NOTES ON THE NE WER REMEDIES.
Toxicology.-This new drug is non-poisonous. As
high as 75 grains (5 grammes) of paraform have been
given to an adult without causing any disagreeable
effects whatever.
PARALDEHYDE.
Paraldehyde, also termed paraldehydum and elalde-
hyde, is a polymeric modification of acetic aldehyde, a
product resulting from the condensation of three mole-
cules of ethyl aldehyde, its formula being (C2H40)3 or
C6 H 2,O3.
Physical Properties.-Paraldehyde is a colorless liquid
having a disagreeable ethereal odor and a burning taste;
it boils at 255 F. (1240 C.), crystallizes at 500 F. (lo
C.), and has a sp. gr. of 0.998.
Solubility.-Elaldezyde is soluble in alcohol, ether,
and the fixed oils; also in water at 600 F. (I5.50 C.), in
the proportion of I to Io.
Therapeutic Applications.-Paraldehyde is chiefly
employed as a hypnotic and antispasmodic. As a
sleep-producing agent it is quite efficient, the charac-
teristic effects becoming manifest in from five to fifteen
minutes. It has produced excellent results in asthma,
and in those cases of simple insomnia accompanied with
convulsive symptoms, such as cough and other distress-
ing phenomena. The drug relieves particularly the ner-
vous insomnia of insanity.
Administration.-This medicament is best given di-
luted, combined with some bitter tincture, in spirits, or
in emulsion, by the rectum or by the mouth. The dose
of it varies from 30 to 60 minims (2 to 4 grammes).
PARTHENICINE.
The alkaloid of Parthenium Ihystcrioplihoris.
Therapeutic Applications. This drug has not been
sufficiently studied, but is said to possess antineuralgic
properties.
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/149/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.