Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 144
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144 NOTES ON THE NEWER REMEDIES.
gramme) once or twice a day, and it is best administered
in wafers (not in pill form) at meal-time.
ORTHIN.
This body is a derivative of phenylhydrazin, its chem-
ical name being ortllholydraziz-para-oxybenZzoic acid.
Physical Properties.z--This drug in the free state is
unstable, but the hydrochlorate is a good and stable
preparation.
Solubility.-Ortin is soluble in water.
Therapeutic Applications.-This remedy has been
found to be a very decided antipyretic, and as such it
has been employed with success in typhoid fever, acute
articular rheumatism, pneumonia, and other febrile dis-
orders.
Administration.-Orthin is given in doses of from 5
to 8 grains (0.30 to 0.50 gramme).
ORTHO-AMIDO-SALICYLIC ACID.
This new substance is salicylic acid in which one atom
of hydrogen has been replaced by NH2.
Physical Properties.- Ort/o-amido-salicylic acid ap-
pears as a white, grayish, amorphous, almost odorless
powder having a sweetish and not unpleasant taste.
Solubility.-This new medicament is insoluble in
alcohol, ether, and water.
Therapeutic Applications. Recent observations have
found this remedy useful in the treatment of subacute
articular rheumatism, and it is recommended as a sub-
stitute for the salicylate of sodium, but as yet no definite
doses have been determined.
OSMIC ACID.
Osmic acid, also termed pcrosmic acid, zyperosmic
acid, and tetroxide of osmium, is chemically constituted
as OsO4.
Physical Properties.-This acid occurs in yellow
crystalline needles having a very strong disagreeable
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/143/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.