Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 148
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148 NOTES ON TILE NEWER REMEDIES.
sin is indicated. Papayotin has likewise been employed
as a local remedy in diphtheria and croup, to dissolve
the membranes. It has been recommended as a solvent
of cerumen. This remedy has been used with marked
success in the treatment of fissure of the tongue when
other agents, such as iodoform, chromic acid, and nitrate
of silver, have failed. Its employment in the treatment
of syphilitic ulcerations of the tongue has given bene-
ficial results.
Administration.-The dose of papain is from I to 5
grains (o.o6 to 0.3 gramme), and it is probably best ad-
ministered in the form of lozenges. Locally, this drug
may be employed in solutions of the strength of 5 per
cent., the applications being carefully made every ten to
fifteen minutes.
PARACOTOIN.
This principle, allied to cotoin, is obtained from the
bark of the para-coto plant, supposed to be the China
coto. Chemical analysis represents the drug as having
a composition of C19H1206.
Physical Properties.-This medicament appears as a
yellowish crystalline powder without odor or taste.
Solubility.-This drug is quite readily soluble in alco-
hol, but difficultly so in ether and in water.
Therapeutic Applications. -Paracotoin is highly
spoken of as a valuable remedy in diarrhea, being
also beneficial in the simple forms of gastric and intes-
tinal catarrhs. It is likewise said to be of service in the
diarrhoea and night-sweats of phthisical patients. It has
been tried successfully in the treatment of Asiatic cholera.
Administration.-Paracotoin is given in the powdered
form or in mixture, the dose being from 2 to 3 grains
(0.12 to 0.18 gramme).
PARACRESALOL.
This substance, also designated by the name of cresalol,
is the salicylale of paracrsol, whose composition is repre-
sented by the formula CH4,-OH,COO,CH4,CH3.
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/147/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.