Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 157
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PHENOSAL YL.
strength of 5 or even Io per cent., and in ointment with
lanolin in the strength of 20 per cent.'
PHENOSALYL.
This new antiseptic combination is obtained by heating
together carbolic, salicylic, and lactic acids, and adding,
when cold, a mixture of menthol and eucalyptol in
glycerin.
Physical Properties.-This drug occurs in the form
of a clear syrupy liquid which crystallizes at low tem-
peratures.
Solubility.-Phenosalyl is readily soluble in warm
water, alcohol, and ether, and soluble in cold water in
the proportion of 7 to Ioo parts.
Therapeutic Applications.-Phenosalyl is said to be
less poisonous than carbolic acid, and is a more effective
germicide. This new remedy has been employed with
satisfactory results as an antiseptic in obstetric practice.
In the form of injections, the use of phenosalyl in bad
cases of purulent cystitis has been attended with excel-
lent results. This agent has also been tried with good
effect in metritis and endometritis, in cutaneous diseases,
particularly eczematous impetigo, in blepharo-adenitis,
and even in conjunctivitis.
Administration.-This drug can be applied in solu-
tions of the strength of from I to 2 per cent. In eye-
affections weaker solutions are preferable-that is, from
1 Other salts of phenocoll, such as the acetate, the carbonate, and the
salicy/ate, are found upon the market, but the first two have not been tried
clinically. The salicylate, however, under the name of salocoll, is said to
have a sweetish taste and to be less soluble than the hydrochloride. It has
recently been recommended as an efficient neuralgic and antirheumatic in
doses of from 15 to 30 grains (I to 2 grammes). In influenza salocoll is
claimed to have acted almost as a specific. Pheeduretin is a derivative of
phenocoll only recently introduced, the chemical nature of which has not
yet been determined. It occurs in the form of white, silky, acicular crystals,
without taste. This new agent is soluble in hot water, but scarcely so in
cold water. This drug possesses diuretic virtues, and has been found to act
favorably in migraine. The dose of pheduretin is set down as from 5 to 15
grains (0.3 to I gramme) twice a day, and it is best given in capsules.I57
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/156/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.