Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 156
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156 NOTES ON THE NEWER REMEDIES.
causes paraplegia, and destroys sensation and motion
when given in sufficiently large doses, especially by
influencing the cord.
Circulation.-Small quantities have no effect on the
circulation; large amounts, however, diminish the blood-
pressure and the pulse-rate through a cardiac action.
This drug exercises no influence upon the blood itself.
Respiration.-Respiration may be slightly accelerated
at first, but is generally depressed under the full action
of phenocoll.
Temperature.-Phenocoll does not seem to affect nor-
mal temperature. It decidedly reduces the heat of fever,
however, the reduction being due mainly to an enormous
diminution of heat-production.
Therapeutic Applications.-Phenocoll hydrochlorate
has valuable therapeutic properties. It has produced
excellent results as an antipyretic in febrile disorders
such as typhoid, in phthisis, and in other pulmonary
affections; as an antirheumatic in many of the acute
forms of rheumatism; and as an antineuralgic, especially
in cases of a hysterical nature. This drug has likewise
been found beneficial in malaria and in influenza. The
antimalarial action of phenocoll appears to have been
established by recent trials; in fact, it has been found
superior to quinine in a large number of instances, with
the advantage that the new remedy does not produce
toxic symptoms. Tinnitus aurium and skin eruptions,
as in the case of quinine, have not been observed under
the use of phenocoll. This medicament is claimed to be
as valuable an antiseptic as iodoform, and as such phe-
nocoll has been locally applied with satisfactory results
in wounds, cutaneous eruptions, acute gonorrhcea, leu-
corrhcea, and other similar disorders.
Administration.-The dose of phenocoll iydrochloride
is from to to 15 grains (0.65 to I gramme) three to five
times a day, and it may be administered in the powdered
form, in aqueous solutions, or in capsules. For local
purposes it may be employed in aqueous solution of the
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/155/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.