Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 133
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ME TIOX YCAFFEINE.--ME TII YLAL.
be better administered early in the afternoon when given
once daily.
Administration.-Me thacetin is given in doses of
from 2 to 5 grains (0.12 to 0.3 gramme), and is best ad-
ministered in mucilage or in cachets.
Toxicology.- Methacetin is apt to depress the heart,
and sometimes collapse accompanied or preceded by
profuse sweating follows the ingestion of the drug.
METHOXYCAFFEINE.
A derivative of caffeine, and found also in other allied
plants. Its chemical composition is CsH,(OCH3)H402.
Physical Properties.-This drug appears in white
crystalline needles having a melting-point of 350.6 F.
(1770 C.).
Therapeutic Applications.-A It/loxycaffcinc has been
found beneficial in cases of migraine and in neuralgias.
It is even said to possess anaesthetic properties superior
to those of cocaine, especially when it is injected hypo-
dermatically.
Administration.-The dose of the medicament is about
4 grains (0.24 gramme).
METHYLAL.
MI'tlylal is also designated by the term mcth/yenzmezthyl-
eticr, and results from the interaction of methylic alcohol,
binoxide of manganese, and sulphuric acid. It is repre-
sented thus: CI-2,(OCH3)2.
Physical Properties.-Methylal is a highly volatile
liquid having a penetrating ethereal odor. Its melting-
point is IO7.6 F. (420 C.), and it has a sp. gr. of 0.855.
Solubility.-This remedy is soluble in alcohol and in
ether, in fatty and ethereal oils, and in water in the pro-
portion of I to 13 parts.
Physiological Action.-This drug diminishes reflex
action and the irritability of the cerebral cortex. In
sufficiently large amounts it acts upon the cardiac gangliaI33
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/132/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.