Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 135
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ME TIYLENE CHLORIDE.
C6H3-N(CH3)2
C6H3 N(CH3)2C1.
Physical Properties.-This drug appears as a bluish
powder composed of scaly crystals, dark green in trans-
verse fracture, and of a bronze-like tinge.
Solubility.-Metzylcene blue is somewhat soluble in
water, and more so when this vehicle contains alcohol.
Therapeutic Applications.-This new remedy has
been largely used with apparent success as an anodyne
in the treatment of rheumatic and neuralgic disorders,
and likewise in pulmonary tuberculosis and scrofula.
Quite recently it has been highly recommended as an
antiperiodic, particularly in cases in which quinine has
failed, and in the local treatment of diphtheria.
Administration.-The dose varies from I I2 to 8
grains (o.o9 to 0.52 gramme), and is best given in
wafers or capsules. Hypodermatically it can be inject-
ed in doses of from to I grain (0.02 to o.o6 gramme).
METHYLENE CHLORIDE.
This drug, which is also known by the name of dich/or-
methane, is obtained by the action of chlorine on mono-
chlormethane or by reducing chloroform by zinc and
hydrochloric acid. It has the composition CHC12.
Physical Properties.- Chloride of mCthylene is a color-
less liquid with an odor resembling that of chloroform.
Its sp. gr. at 590 F. (I5o C.) is 13.6; it melts at io6 F.
(41.6 C.).
Solubility.-This drug is soluble in alcohol and in
ether.
Therapeutic Applications.-Mkct/hylene chloride has
been recommended as a substitute for chloroform, but
is now chiefly employed as a local anaesthetic.I35
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/134/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.