Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 132
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132 NO TES ONA THE NE WER REMEDIES.
Solubility.-Metaldehyd is readily soluble in hot al-
cohol and ether, but insoluble in water.
Therapeutic Applications.-This medicament pos-
sesses hypnotic virtues similar to those of paraldehyd,
but its use in practical medicine has not been very ex-
tensive.
Administration.-The dose of metaldehyd may be
said to be more or less the same as that of paralde-
hyd.
METAMIDOPHENYLPARAMETHOXYCHINOLIN.
Therapeutic Applications.-This drug has recently
been recommended as an antiperiodic in the treatment of
malarial diseases, in which it is said to equal quinine.
Administration.-It has been given in doses of from
3 - to 74 grains (0.25 to 0.50 gramme).
METHACETIN.
This name is applied to para-acetanisidin or para-ozy-
methylacetanilid, or acctyl- mzectly/-para-azmido-phcItol, bei ng
thus chemically constituted: C61,,.OCH3:NHCHI3CO.
Physical Properties.-MAlcthacctin occurs in crystal-
line scales, almost colorless or somewhat reddish, and
without taste. It melts at 260.60 1. (127 C.).
Solubility.-This drug is readily soluble in alcohol,
chloroform, glycerin, and warm fatty oils; also in water
in the proportion of I to 260 parts.
Physiological Action.-Large doses cause death pre-
ceded by convulsions. It is said to reduce the bodily
temperature by diminishing both heat-production and
heat-distribution.
Therapeutic Applications.-Methacetin has been
much lauded as an antiseptic and analgesic. It is espe-
cially suitable in the treatment of febrile diseases of chil-
dren. This remedy has proved to be of value in rheu-
matic and tubercular affections. It has given good
results in the pyrexia of phthisis, in which it is said to
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/131/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.