Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 113
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H YOSCINE.
amin hydrochloride is represented by the formula NH2-
OHHCL.
Physical Properties.-This salt appears in colorless
crystals resembling those of the chloride of ammonium.
Solubility.-This drug is soluble in water and in
glycerin.
Therapeutic Applications.-Hydroc/zloride of hy-
droxylamzin has been recommended as a substitute for
anthrarobin, chrysarobin, and pyrogallol in the treatment
of skin diseases. The drug has certainly done good ser-
vice in lupus, and especially in parasitic disorders, such
as psoriasis, mycosis tonsurans, sycosis parasitica, etc.
Administration.-This remedy is best applied locally
in solutions of the strength of I : 000oo.
HYOSCINE.
An alkaloid extracted from the seeds of Hyoscyamus
niger. The chemical nature of the principle is repre-
sented by the formula C17HiNO3.
Physical Properties.-Hyoscini? itself is a non-crys-
tallizable body, but the hjydrobromide occurs in fine col-
orless crystals of a rhombic form.
Solubility.-This salt is soluble in water and in alco-
hol. The solution has a bitter and slightly pungent
taste.
Physiological Action.-This drug causes in the lower
animals loss of motor power and of reflex action by in-
fluencing the centres of the cord. It may sometimes
produce wild delirium, although its effect usually is that
of a depressant to the brain, causing sleep. Upon the
circulation this drug appears to exercise a feeble influ-
ence, although in large amounts it is said to paralyze
the vaso-motor system. This agent diminishes the
pulse-rate generally, but it may accelerate it. The res-
piration is depressed and the pupil slightly dilated under
the action of hyoscine.
Therapeutic Applications.-This drug is an excellentII3
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/112/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.