Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 115
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ICHTH YOL.
45 grains (i to 3 grammes), and may be given in water
or in solution with orange-peel syrup.'
ICHTHYOL.
This substance is obtained from a bituminous oil by
distillation, and contains about 15 per cent. of sulphur.
It is the ammoizum izch/hyo/lsulphonatc, its chemical com-
position being represented as C2sH36SO,6(NH4)2.
Physical Properties.-This drug is soluble in water,
and partly so in alcohol, ether, and petroleum benzene.
Therapeutic Applications.- The therapeutic uses of
ichthyol are quite extensive. The drug is certainly ad-
vantageous as an antiphlogistic and alterative and as an
astringent, tonic, and anodyne. This medicament is of
special value in a variety of cutaneous affections. While
not a true germicide, it is said to arrest the development
of bacteria. Internally, the remedy has given good re-
sults in the treatment of diseases of the gastro-intestinal
tract, of the kidneys, in rheumatism, in syphilitic dis-
orders, and even in leprosy. Its use in diseases of the
respiratory organs has been recommended as an inhala-
tion. Ichthyol has been found almost a specific in mos-
quito-bites, and of incalculable benefit in the abortive
treatment of erysipelas. Hypodermatically, ichthyol is
said to have acted well in cases of neuralgia.
Administration.-The internal daily dose of ichthyol
is from Io to 30 grains (o.6 to 2 grammes), and is best
administered in capsules or in pill form. For external
application there may be employed solutions and oint-
ments, in chloroform, glycerin, and lanolin respectively,
of the strength of from Io to 50 per cent.
1 Bu/l-hIypzal is a combination of antipyrin and butyl-chloral, analogous
to hypnal. This new remedy occurs in the form of colorless crystals hav-
ing an insipid bIitter taste and an odor resembling that of butyl-chloral. It
melts at 1580 F. (700 C.), and is soluble in alcohol, ether, benzene, and
chloroform. Perchloride of iron gives with butyl-hypnal a red solution.
This latter substance is precipitated by picric acid; with alkalies it is de-
composed into antipyrin, alkaline formate, and propyl chloroform. The
medicament in question has not been tried in practical medicine, but it
appears to have properties similar to those of chloral.II5
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/114/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.