Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 200
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200 NOTES ON THE NE WER REMEDIES.
in tuberculous abscesses is followed by rapid healing.
The remedy is also said to be of great service in fungous
adenitis, actinomycosis, and lupus. Its use is suggested
in the treatment of local tuberculosis of the soft tissues.
Locally applied in the form of ointment or suppositories,
teucrin is recommended in the treatment of various
forms of hemorrhoids. It is said greatly to relieve the
local trouble.
Administration.-Teucrin has been employed hypo-
dermatically in doses of as high as 45 grains (3 grammes).
For local applications Io grains (o.6 gramme) may be used
as an ointment with lanolin and olive oil, once daily.
THALLIN.
This compound, which is obtained by heating together
para-amidoanisol and acrolein in the presence of some
oxidizing agent, is the tetra -zydropara-met/yl-oxychinolin
or tetra-kydroparachinanisol, whose chemical constitution
is represented by the formula C,.Hn1NO.
Physical Properties.-Thallin is a liquid at ordinary
temperature, but when cooled appears in the form of a
yellowish-white crystalline powder having a saline, bitter
taste and an odor resembling that of the coumarin bean.
Solubility.-This medicament is soluble in water in
the proportion of I to 5 parts. The two chief salts used
in medicine, the sulphate and the tartrate, are both soluble
in water in the proportion of I to 7 and I to IO parts re-
spectively, and slightly soluble in alcohol.
Physiological Action.-In large doses thallin acts as
a depressant to the circulation, lowering arterial pressure
by influencing the heart and the vaso-motor system. On
normal temperature the drug exercises but little if any
influence. It, however, reduces febrile temperature by
increasing heat-dissipation. Thallin also acts as an anti-
septic, and appears to exert some influence as a diuretic,
producing at the same time a dark-brown color of the
urine. It is said to decrease the elimination of carbon
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/199/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.