Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 194
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NOTES ON THEE NEWER REMEDIES.
SULPHAMINOL.
Sulphaminol is the name applied to thioxydiphenyl-
amin, obtained by the action of sulphur on the salts of
metaoxydiphenylamine.
Physical Properties.-This drug appears as a pale-
yellow, odorless, and tasteless powder having a melting-
point of 311 F. (1550 C.). The solutions are of a pale-
yellow color.
Solubility.-Sulphaminol is freely soluble in alkalies,
alcohol, and acetic acid; it is insoluble in water.
Therapeutic Applications. - Thioxydiphenylamin
possesses good antiseptic properties, and has been em-
ployed with favorable results as a substitute for iodoform
in the treatment of wounds, ulcers, and other similar dis-
orders. It has been especially used in rhinological
practice. Internally, it has been found beneficial in
cystitis.
Administration.-Sulphaminol is given in single or
daily doses of 4 grains (0.24 gramme) and 15 grains (I
gramme) respectively. It is generally applied, however,
as a dusting-powder.'
SULPHONAL.'
This is diethylsulpon-dimethyl-methane, obtained by
the interaction of anhydrous mercaptan and anhydrous
acetone in the presence of hydrochloric acid gas. The
formula of this drug is (CH3)2C(SOCH,)2.
Physical Properties.-Sulphonal is a colorless, odor-
less substance made up of prismatic crystals melting at
from 2570 to 258.8o F. (125' to 126 C.).
1 Derivatives of sulphaminol (such as sulphaminol creosote, sulphaminol-
eucalyptol, sulphaminol guaiacol, and sulhaminzol menhol) are being tried
at present in the treatment of laryngeal tuberculosis and in rhino-laryngology.
2 Sulphonal must not be confounded with solphinol. This latter drug is
said to be a mixture of borax, boric acid, and alkaline sulphites, occurring as
a white, crystalline, odorless powder, soluble in Io parts of water and in 20
parts of glycerirr. A solution of the strength of from 2 to to per cent. is
said to act as a good disinfectant in the treatment of wounds.I194
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/193/: accessed April 30, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.