Dallas Voice (Dallas, Tex.), Vol. 8, No. 53, Ed. 1 Friday, April 24, 1992 Page: 1 of 40
forty pages : ill. 15 x 12View a full description of this newspaper.
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FDA expands anti-HIV arsenal
Panel relieved with final
results from DDI study
o
By Dennis Vercher i
Several members of a review panel «
which last July voted to recommend S
limited use of the anti-HIV drug DDI |
now say their decision, controversial in 1
some medical circles, is vindicated by £
new data the government released on •
Monday. |
The review panel said DDI, or 2
didanosine, "demonstrated anticipated Z
clinical benefit" which regulators had £
hoped for in granting early release of the |
medication based only on preliminary ;
findings. The completed study, they £
noted, showed DDI was effective in ;
slowing the replication of HIV, the AIDS
virus, inside the body.
But the review panel stopped short
of extending the drug's availability to
patients who had not first tried the
CONTINUED ON PAGE 12
An electron micrograph shows a CD-4 immune system cell infected with human
immunodeficiency viruses. All three anti-HIV drugs now available — AZT, DDI and
DDC — inhibit the ability of the virus to reproduce by suppressing a key enzyme
called reverse transcriptase. Without the enzyme, the vims cannot bind its genetic
material to that of the host cell, a necessary step in viral replication.
DDC becomes 3rd HIV
drug approved in U.S.
By Dennis Vercher
A government advisory panel on
Tuesday recommended that the Food
and Drug Administration grant limited
approval to the antiviral medication
DDC, or dideoxycytidine.
Using a new method designed to
speed AIDS drugs to the marketplace,
the panel — as in the case of last
MEDICINE
summer's recommendations for a similar
drug, DDI (see related story) — based
its recommendations on preliminary
evidence but said DDC should be
withdrawn from the market if studies
now underway ultimately fail to prove
the compound’s effectiveness.
The panel recommended that the
FDA approve use of DDC only in
CONTINUED ON PAGE 12
Sandy Duncan
Duncan pushes for better
awareness and research
She hopes Heartstrings will help get people Involved
By Dennis Vercher
“I was doing The Hogan Family at
the time,” recalls film and television star
Sandy Duncan. “Two of my closest
friends had died [of AIDS] and I was in
kind of a low place in terms of what
could be done.”
A telephone call from an official of
the Design Industries Foundation for
AIDS made the difference, she says.
Duncan grew enthusiastic as the official
described DIFFA’s plan to institute a
nationwide touring performance of
INTERVIEW
Heart Strings, a musical addressing many
aspects of the AIDS crisis with the goal
of raising awareness across a broad
CONTINUED ON PAGE 24
Inside —
NEWS: England to proceed with
DPD application, training;
Leaders react to Bush statement
on domestic partners; More........
FILM: USA Film Festival features
some offerings of interest
todays and lesbians — although
fewer than in recent past..............
IMAGES: Coming Out and
dealing with homophobia;
Agency begins program for
women...........................................
THEATER: A review of The
Baltimore Waltz, lesbian-
directed production onstage at
Houston's Alley.............................
3
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Vercher, Dennis. Dallas Voice (Dallas, Tex.), Vol. 8, No. 53, Ed. 1 Friday, April 24, 1992, newspaper, April 24, 1992; (https://texashistory.unt.edu/ark:/67531/metapth615912/m1/1/: accessed May 21, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting UNT Libraries Special Collections.