Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 84
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84 NOTES ON THE NEWER REMEDIES.
Therapeutic Applications.-This remedy is claimed
to possess energetic disinfectant properties, but it has
had no very extensive use.
Administration.-Disinfectol has been employed
locally in the form of emulsion of a strength of from 2
to 5 per cent.
DIURETIN.
The sodio-salicy/ate of theobromine or the salicylate of
theobromine and sodium is designated by the name of
diuretin. This combination, which is supposed to con-
tain 49.7 per cent. of theobromine and 38.1 per cent. of
salicylic acid, is represented by the formula CHN40,-
Na,C6H40 H CO-ONa.
Physical Properties.-This salt appears as a white
powder.
Solubility.-This compound is soluble in hot water
and in warm alcohol, but is insoluble in chloroform and
ether.
Physiological Action.-The chief action of this
double salt is that of a diuretic, stimulating directly, it
is claimed, the secreting epithelium of the kidney.
Therapeutic Applications. Diuretin is employed
extensively as a diuretic, especially in dropsies of cardiac
origin. Its effects are said to have been satisfactory in
most instances.
Administration.-This drug is best given in pill form,
but may likewise be administered in powder dissolved in
peppermint-water. The dose is 15 grains (I gramme)
five or six times a day.
DUBOISINE.
The alkaloidal principle yielded by Duboisia myopo-
roides; it is obtained from the leaves of the plant, and is
represented by the formula CH23NO0.
Therapeutic Applications.-The sulphate of duboisine,
the salt generally used in practical medicine, has of late
been employed not only as a mydriatic in place of atropine,
but also, with asserted success, as a sedative and hyp-
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/83/?q=cerna: accessed May 1, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.