Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 223
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APPENDIX.
ARECOLINE.
This substance is said to be the active principle of
areca-nut, or Areca catechu. Its composition is repre-
sented by the formula C8H13NO.
Physical Properties. In the pure state this drug ap-
pears in the form of a volatile fluid, strongly alkaline
and colorless. The Iydrobromate of arecoline is a crys-
talline body.
Solubility.-This remedy is soluble in alcohol, ether,
chloroform, and water, in all proportions.
Physiological Action.-Arecoline is quite poisonous,
one of its chief effects being a marked increase of intes-
tinal peristalsis. This remedy acts as a toeniafuge. As
a laxative it is said to be as powerful as eserine, and ten
times as strong as pilocarpine.
Therapeutic Applications.-Arecoline has so far been
used in veterinary practice only.
Administration.-This drug is best administered in
the form of the hydrobromate. It is given, for the horse,
in single doses of i 3 grains (o.Io gramme), and for the
ox in quantities of 34 grains (0.25 gramme).
PSEUDOHYOSCYAMINE.
This-new alkaloid has recently been discovered in the
Duboisia myoporoides.. Chemically this alkaloid is repre-
sented by the formula C,1H23NO3.
Physical Properties. This drug occurs in the form
of small yellow needles having an acrid, bitter taste, and
223
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/222/?q=cerna: accessed May 22, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.