Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 88
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88 NOTES OAN THE NEWER REMEDIES.
tion of the automatic cardiac centres; the slowing which
follows depends on a diminished irritability of the cardiac
muscle. This drug has no effect apparently on the vagi,
the cardio-dilator centres, or the peripheral vaso-dilator
nerves.
Respiration.-Action uncertain, but bromide of ethyl
usually kills by respiratory failure.
Therapeutic Applications.-This drug is employed as
an anaesthetic for cases of minor surgery. The anas-
thesia produced by the drug is prompt, being effected in
the course of from a half to one minute, but soon passes
off after the removal of the remedy. Ethyl bromide is
therefore inferior, from a practical point of view, to
chloroform, but is often preferable to the latter agent.
Administration.-The dose of bromide of ethyl is
from 3 to 6 drachms (I 11.25 to 22.50 grammes), adminis-
tered by inhalation.
Toxicology. Nausea and vomiting sometimes follow
the administration of ethyl bromide. An unpleasant
garlic-like odor of the breath and a similar taste in the
mouth often remain for several days after the use of the
drug. Bromide of ethyl is apt to produce -nervous
twitchings and even tetanic spasms. It has caused death.
ETHYL CHLORIDE.
This new anaesthetic is said to be produced by the
action of hydrochloric acid upon alcohol. It is repre-
sented by the formula C2,HC1.
Physical Properties.-This drug occurs as a colorless,
inflammable, volatile liquid of a not unpleasant odor.
It boils between 50o and 530 F. (Ioo to I2 C.) and burns
with a green flame.
Physiological Action. This drug acts as a fugacious
general anaesthetic. The anasthesia produced by it,
however, is usually accompanied by a fall of the arte-
rial pressure and a decrease in heart-beat, due probably
to a direct cardiac action. It increases at first both the
rate and depth of the respiratory movements, followed
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/87/: accessed April 25, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.