Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 80
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80 NO TES ON THE NE WER REMEDIES.
rinsed with 2 per cent. creolin-water, and to the milk
of the bottle is then added I drop (o.o6 gramme) of the
drug. In this manner the taste of the antiseptic is
almost wholly destroyed.'
CREOSOTAL.
This body is obtained by the action of carbon dioxide
upon creosote. It is the carbonate of creosote.
Physical Properties.- Creosotal occurs in the form of
a viscid oily liquid, without odor. It becomes quite fluid
on the application of moderate heat, and has a sp. gr. of
1.165 at 590 F. (15 C.).
Solubility.-- Creosote carbonate is soluble in alcohol,
ether, chloroform, and benzene; it is insoluble in water.
Physiological Action.-When ingested by the stom-
ach, even in large doses, this drug exercises no delete-
rious influence. It is said to be decomposed in the
intestines into its components, creosote and carbon
dioxide. The former constituent is found in the urine
about half an hour after the ingestion of creosotal.
Therapeutic Applications.-Carbonate of creosote
has been employed with alleged success in the treatment
of tuberculosis.
Administration.-Creosotal may be administered in
daily doses of from 7 2 to 15 drachms (Io to 20
grammes).
CYTISINE.
Various species of Cytisus, especially Cytisus laburnum,
yield an alkaloid known as cytisine, whose chemical com-
position is C11H1,N20.
1 The name of sanatol has been applied to a thin blackish-brown liquid,
soluble in water with a milky turbidity. It is said to be prepared from a
so-called ioo per cent. carbolic acid and an excess of concentrated sul.
phuric acid. The new agent is claimed to be a decided disinfectant; I
and 2 per cent. solutions, respectively, have been found to destroy the
vibrios of cholera and bacterium coli commune in half a minute. Sanatol
has not yet been tried in practical medicine.
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/79/: accessed March 29, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.